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Math Biology Seminar: Insights into viral coinfections from mathematical models

Author: Lona

Speaker: Hana Dobrovolny from Texas Christian University

Abstract: Many patients hospitalized with influenza-like illnesses have been found to be infected with more than one virus. Clinical studies have found mixed results when investigating whether coinfections lead to more severe disease, with some studies even suggesting that coinfections are less severe than mono-infections. In vitro studies also show mixed results with some viruses being suppressed in coinfections and others being enhanced. In this presentation, I will discuss a series of mathematical models that have helped us understand the mechanisms underlying some of the dynamics observed in viral coinfections.